iPQB Faculty
Cell Biology & Genetics:
David Agard | Image
Professor, Biochemistry & Biophysics
agard@msg.ucsf.edu | Agard Lab
Structure, function, and folding of proteins, chromosomes, and centrosomes
Nadav Ahituv | Image
Assistant Professor, Bioengineering and Therapeutic Sciences
nadav.ahituv@ucsf.edu |
Deciphering the role of gene regulatory sequences in human biology and disease
Bruce Conklin | Image
Associate Professor, Gladstone Institute of Cardiovascular Disease, Medicine & Pharmacology
bconklin@gladstone.ucsf.edu | Link
Combining the tools of molecular biology, genetics, bioinformatics, and physiology to answer fundamental issues in pharmacology.
Joe DeRisi | Image
Hughes Investigator, Associate Professor, Biochemistry & Biophysics
joe@derisilab.ucsf.edu | DeRisi Lab
Malaria gene expression profiling, functional genomics, microarrays
Tejal Desai | Image
Professor, Department of Physiology & Division of Bioengineering
tejal.desai@ucsf.edu | Desai Lab
Micro and nanofabrication approaches to tissue engineering scaffold design; implantable and oral drug delivery platforms; Surface modification for enhanced biorecognition, targeting, and biocompatibility.
Robert Edwards | Image
Professor, Neurology
robert.edwards@ucsf.edu | Link
Molecular analysis of neurotransmitter release; biophysical methods to study mechanisms underlying active transport.
Bob Farese | Image
Professor of Medicine, Biochemistry and Biophysics
bfarese@gladstone.ucsf.edu |
Cell Biology of Energy Metabolism
Kathy Giacomini | Image
Professor, Bioengineering and Therapeutic Sciences, Cellular & Molecular Pharmacology, and Pharmaceutical Chemistry
kmg@itsa.ucsf.edu | Link
Molecular mechanisms of nucleosides transporters and organic cations, and pharmacogenomics
Carol Gross | Image
Professor, Cell & Tissue Biology
cgross@cgl.ucsf.edu | Gross Lab
Regulation of gene expression.
John Gross | Image
Assistant Professor, Pharmaceutical Chemistry
jdgross@picasso.ucsf.edu | Gross Lab
Structural biology and mechanism of gene specific translation control; RNA turnover; macromolecular NMR spectroscopy.
Lily Jan | Image
Professor, Department of Physiology & Howard Hughes
lily.jan@ucsf.edu | Jan Lab
Structure-function studies of potassium channels in mammalian heart and hippocampus.
Cynthia Kenyon | Image
Professor, Biochemistry & Biophysics
ckenyon@biochem.ucsf.edu | Kenyon Lab
Genes and Cells that Regulate the Lifespan of C. elegans
Juan Korenbrot | Image
Professor, Physiology
juan.korenbrot@ucsf.edu | Link
Transduction in photoreceptors and functional development of the retina.
Nevan Krogan | Image
Assistant Professor, Cellular and Molecular Pharmacology
krogan@cmp.ucsf.edu | Krogan Lab
Functional Insights from Genetic and Physical Interaction Maps
Wallace Marshall | Image
Assistant Professor in Residence, Biochemistry & Biophysics
wmarshall@biochem.ucsf.edu | Marshall Lab
How the three-dimensional geometry of cells can be generated from the one-dimensional genome. Engineering and physical principles that underlie cellular morphogenesis.
Michael McManus | Image
Assistant Professor, Microbiology & Immunology
mmcmanus@diabetes.ucsf.edu | McManus Lab
Mammalian microRNA and RNA Interference Pathways
Daniel Minor | Image
Assistant Professor, Departments of Biochemistry and Biophysics, and Cellular and Molecular Pharmacology Investigator, Cardiovascular Research Institute
daniel.minor@ucsf.edu | Minor Lab
Molecular Basis of electrical signalling; Ion channel structure, function, and modulation. Membrane protein structure.
Dyche Mullins | Image
Assistant Professor, Cellular & Molecular Pharmacology
dyche@mullinslab.ucsf.edu | Mullins Lab
Cellular signaling systems controlling the three-dimensional organization of the actin cytoskeleton.
Neil Risch | Image
Professor and Director, Center for Human Genetics
rischn@humgen.ucsf.edu | Link
Genetic epidemiology of complex diseases in ethnic populations
Saunak Sen | Image
Associate Professor in Residence, Epidemiology and Biostatistics
sen@biostat.ucsf.edu |
Genetic analysis of complex traits, statistical genetics/genomics, Bayesian statistics, statistical computing
Ron Vale | Image
Professor and Chair, Cellular & Molecular Pharmacology
vale@cmp.ucsf.edu | Vale Lab
Mechanism of microtubule-based motor proteins.
Alan Verkman | Image
Professor in Residence, Nephrology
verkman@itsa.ucsf.edu | Verkman Lab
Molecular mechanisms of water and anion transport; novel fluorescence methods to study living cells.
Jeff Wall | Image
Assistant Professor, Institute for Human Genetics
wallj@humgen.ucsf.edu
Evolutionary and Human Genetics
Peter Walter | Image
Professor, Biochemistry & Biophysics
walter@cgl.ucsf.edu | Walter Lab
Protein sorting and organelle biogenesis.
Orion Weiner | Image
Assistant Professor in Residence, Cardiovascular Research Institute
orion.weiner@ucsf.edu | Weiner Lab
How cells generate polarity; cell migration; chemotaxis.
Jonathan Weissman | Image
Professor, Department of Cellular and Molecular Pharmacology
weissman@cmp.ucsf.edu | Weissman Lab
Mechanism of molecular chaperones and protein folding in vivo.
Structural & Chemical Biology:
David Agard | Image
Professor, Biochemistry & Biophysics
agard@msg.ucsf.edu | Agard Lab
Structure, function, and folding of proteins, chromosomes, and centrosomes
Patricia Babbitt | Image
Professor, Bioengineering and Therapeutic Sciences and Pharmaceutical Chemistry
babbitt@cgl.ucsf.edu | Babbitt Lab
Computational and experimental analysis of protein superfamilies for functional inference and enzyme design
Yifan Cheng | Image
Professor, Biochemistry & Biophysics
ycheng@biochem.ucsf.edu | Cheng Lab
Using molecular electron microscopy as a tool, we are interested in the structural and functional characterizations of macromolecules assemblies, including endocytotic machinery, clathrin coated vesicles, and protein degradation machinery, proteasome.
Charles Craik | Image
Professor, Pharmaceutical Chemistry
craik@cgl.ucsf.edu | Craik Lab
Protein engineering, mutagenesis, heterologous gene expression, enzyme mechanisms and inhibitor design.
Ken Dill | Image
Professor, Pharmaceutical Chemistry
dill@maxwell.ucsf.edu | Dill Group
Statistical mechanics of biomolecules, protein and RNA folding, solvation
Pamela England | Image
Assistant Professor, Pharmaceutical Chemistry
england@picasso.ucsf.edu | England Group
Ion channel structure-function, synaptic plasticity.
Robert Fletterick | Image
Professor, Biochemistry & Biophysics
flett@msg.ucsf.edu | Fletterick Lab
Structure and function of proteins, using x-ray crystallography and molecular genetics.
Alan Frankel | Image
Professor, Biochemistry & Biophysics
frankel@cgl.ucsf.edu | Frankel Lab
RNA-protein recognition; structures of peptide-RNA complexes; prediction of RNA structure; structure and function of HIV Tat protein.
Danica Galonic Fujimori
Assistant Professor, Cellular and Molecular Pharmacology, Pharmaceutical Chemistry
fujimori@cmp.ucsf.edu |
Chemical approaches to investigate enzymatic function
Zev Gartner
Assistant Professor, Pharmaceutical Chemistry
zev.gartner@ucsf.edu |
New methods for synthesizing and perturbing functional biological structures
Carol Gross | Image
Professor, Cell & Tissue Biology
cgross@cgl.ucsf.edu | Gross Lab
Regulation of gene expression.
John Gross | Image
Assistant Professor, Pharmaceutical Chemistry
jdgross@picasso.ucsf.edu | Gross Lab
Structural biology and mechanism of gene specific translation control; RNA turnover; macromolecular NMR spectroscopy.
Bo Huang
,
bhuang@picasso.ucsf.edu |
Using super-resolution optical microscopy to understand the molecular architecture inside a cell.
Wendell Lim | Image
Professor, Cellular & Molecular Pharmacology
lim@cmp.ucsf.edu | Lim Lab
Structure-function studies of potassium channels in mammalian heart and hippocampus.
Susan Miller | Image
Associate Professor, Pharmaceutical Chemistry
smiller@cgl.ucsf.edu | Link
Enzyme mechanisms emphasizing redox systems, protein-protein interactions and structure-function relationships of mechanisms of regulation and catalysis.
Daniel Minor | Image
Assistant Professor, Departments of Biochemistry and Biophysics, and Cellular and Molecular Pharmacology Investigator, Cardiovascular Research Institute
daniel.minor@ucsf.edu | Minor Lab
Molecular Basis of electrical signalling; Ion channel structure, function, and modulation. Membrane protein structure.
Geeta Narlikar | Image
Assistant Professor, Biochemistry & Biophysics
gnarlikar@biochem.ucsf.edu | Link
Mechanisms of chromatin remodeling
Richard Shafer
Professor, Pharmaceutical Chemistry
shafer@cgl.ucsf.edu
Biophysical chemistry of DNA and drug-DNA complexes.
Brian Shoichet | Image
Professor, Pharmaceutical Chemistry
shoichet@cgl.ucsf.edu | Shoichet Lab
Molecular docking, structure-based inhibitor discovery, beta-lactamase activity-stability-evolution, and crystallography.
Kevan Shokat | Image
Professor, Cellular & Molecular Pharmacology
shokat@cmp.ucsf.edu | Shokat Lab
Chemical tools for studying cellular signaling cascades; protein engineering; organic synthesis.
Robert Stroud | Image
Professor, Department of Biochemistry & Biophysics
stroud@msg.ucsf.edu | Stroud Lab
Structure and function of cell-surface receptors; communication between macromolecules; mechanisms of transmembrane signaling; drug design.
James Wells | Image
Professor, Pharmaceutical Chemistry
jim.wells@ucsf.edu | Link
Small molecule drug discovery; drug mechanisms as they relate to apoptosis and cancer.
Complex Systems & Synthetic Biology:
Nadav Ahituv | Image
Assistant Professor, Bioengineering and Therapeutic Sciences
nadav.ahituv@ucsf.edu |
Deciphering the role of gene regulatory sequences in human biology and disease
Joe DeRisi | Image
Hughes Investigator, Associate Professor, Biochemistry & Biophysics
joe@derisilab.ucsf.edu | DeRisi Lab
Malaria gene expression profiling, functional genomics, microarrays
Tejal Desai | Image
Professor, Department of Physiology & Division of Bioengineering
tejal.desai@ucsf.edu | Desai Lab
Micro and nanofabrication approaches to tissue engineering scaffold design; implantable and oral drug delivery platforms; Surface modification for enhanced biorecognition, targeting, and biocompatibility.
Hana El-Samad | Image
Assistant Professor, Biochemistry & Biophysics
helsamad@biochem.ucsf.edu |
Computational biology/stochastic biological dynamics; modeling of biological systems
Loren Frank | Image
Assistant Professor, Physiology
loren@phy.ucsf.edu | Link
The study of the role of the hippocampus and adjacent cortical regions in learning and memory.
Zev Gartner
Assistant Professor, Pharmaceutical Chemistry
zev.gartner@ucsf.edu |
New methods for synthesizing and perturbing functional biological structures
Carol Gross | Image
Professor, Cell & Tissue Biology
cgross@cgl.ucsf.edu | Gross Lab
Regulation of gene expression.
John Gross | Image
Assistant Professor, Pharmaceutical Chemistry
jdgross@picasso.ucsf.edu | Gross Lab
Structural biology and mechanism of gene specific translation control; RNA turnover; macromolecular NMR spectroscopy.
Tanja Kortemme | Image
Assistant Professor, Bioengineering and Therapeutic Sciences
kortemme@cgl.ucsf.edu | Kortemme Lab
Computational biology, prediction and design of protein interactions and networks, synthetic biology
Hao Li | Image
Associate Professor, Biochemistry & Biophysics, Pharmaceutical Chemistry, Cellular & Molecular Pharmacology
haoli@genome.ucsf.edu | Li Lab
Bioinformatics, genome sequence analysis, gene regulation
Wendell Lim | Image
Professor, Cellular & Molecular Pharmacology
lim@cmp.ucsf.edu | Lim Lab
Structure-function studies of potassium channels in mammalian heart and hippocampus.
Hiten Madhani | Image
Professor, Biochemistry & Biophysics
hiten.madhani@ucsf.edu |
We seek to use quantitative approaches discover novel mechanisms by which cells select regions of the genome to express into protein.
Dyche Mullins | Image
Assistant Professor, Cellular & Molecular Pharmacology
dyche@mullinslab.ucsf.edu | Mullins Lab
Cellular signaling systems controlling the three-dimensional organization of the actin cytoskeleton.
Sarah Nelson | Image
Professor, Bioengineering and Therapeutic Sciences
sarah.nelson@radiology.ucsf.edu |
Development of techniques for the acquisition, reconstruction, and quantitative analysis of in vivo imaging and spectral data.
Philip Sabes | Image
Associate Professor, Physiology
sabes@phy.ucsf.edu | Sabes Lab
Learning and adaptation in sensorimotor control: human psychophysics, neurophysiology, and computational methods.
Andrej Sali | Image
Professor, Bioengineering and Therapeutic Sciences
sali@salilab.org | Sali Lab
Computation grounded in the laws of physics and evolution to study the structure and function of proteins
Chao Tang | Image
Professor, Bioengineering and Therapeutic Sciences & Biochemistry and Biophysics
chao.tang@ucsf.edu | Tang Lab
Design and organization principles of biological systems; quantitative study and systems analysis of biological networks; systems biology.
Ron Vale | Image
Professor and Chair, Cellular & Molecular Pharmacology
vale@cmp.ucsf.edu | Vale Lab
Mechanism of microtubule-based motor proteins.
Christopher Voigt | Image
Associate Professor, Pharmaceutical Chemistry
cavoigt@picasso.ucsf.edu | Voigt Lab
Design and evolution of gene circuits and pathways.
Jonathan Weissman | Image
Professor, Department of Cellular and Molecular Pharmacology
weissman@cmp.ucsf.edu | Weissman Lab
Mechanism of molecular chaperones and protein folding in vivo.
Bioinformatics & Computational Biology:
Nadav Ahituv | Image
Assistant Professor, Bioengineering and Therapeutic Sciences
nadav.ahituv@ucsf.edu |
Deciphering the role of gene regulatory sequences in human biology and disease
Patricia Babbitt | Image
Professor, Bioengineering and Therapeutic Sciences and Pharmaceutical Chemistry
babbitt@cgl.ucsf.edu | Babbitt Lab
Computational and experimental analysis of protein superfamilies for functional inference and enzyme design
Joe DeRisi | Image
Hughes Investigator, Associate Professor, Biochemistry & Biophysics
joe@derisilab.ucsf.edu | DeRisi Lab
Malaria gene expression profiling, functional genomics, microarrays
Ken Dill | Image
Professor, Pharmaceutical Chemistry
dill@maxwell.ucsf.edu | Dill Group
Statistical mechanics of biomolecules, protein and RNA folding, solvation
Hana El-Samad | Image
Assistant Professor, Biochemistry & Biophysics
helsamad@biochem.ucsf.edu |
Computational biology/stochastic biological dynamics; modeling of biological systems
Thomas Ferrin | Image
Professor, Pharmaceutical Chemistry & Bioengineering and Therapeutic Sciences. Director, Resource for Biocomputing, Visualization, and Informatics
tef@cgl.ucsf.edu | Computer Graphics Lab
Molecular graphics; scientific visualization; computational chemistry; bioinformatics; structure-based drug design
Matthew Jacobson | Image
Associate Professor, Pharmaceutical Chemistry
matt@cgl.ucsf.edu | Jacobson Group
Fundamental principles of physical chemistry and biological applications specifically modeling proteins and protein-ligand complexes using physics-based methods
Ajay Jain | Image
Professor, Cancer Research Institute, Bioengineering and Therapeutic Sciences, Laboratory Medicine, UCSF Helen Diller Family Comprehensive Cancer Center
ajain@jainlab.org | Jain Lab
Computational approaches for drug design, molecular docking, molecular similarity, predictive pharmacology, and modeling genomic and molecular phenomena involved in cancer.
Tanja Kortemme | Image
Assistant Professor, Bioengineering and Therapeutic Sciences
kortemme@cgl.ucsf.edu | Kortemme Lab
Computational biology, prediction and design of protein interactions and networks, synthetic biology
Nevan Krogan | Image
Assistant Professor, Cellular and Molecular Pharmacology
krogan@cmp.ucsf.edu | Krogan Lab
Functional Insights from Genetic and Physical Interaction Maps
Hao Li | Image
Associate Professor, Biochemistry & Biophysics, Pharmaceutical Chemistry, Cellular & Molecular Pharmacology
haoli@genome.ucsf.edu | Li Lab
Bioinformatics, genome sequence analysis, gene regulation
Michael McManus | Image
Assistant Professor, Microbiology & Immunology
mmcmanus@diabetes.ucsf.edu | McManus Lab
Mammalian microRNA and RNA Interference Pathways
Katie Pollard | Image
Associate Investigator/Professor, Gladstone Institute/Biostatistics/Institute for Human Genetics
kpollard@gladstone.ucsf.edu |
Evolutionary computational biology
Andrej Sali | Image
Professor, Bioengineering and Therapeutic Sciences
sali@salilab.org | Sali Lab
Computation grounded in the laws of physics and evolution to study the structure and function of proteins
Mark Segal | Image
Professor, Epidemiology & Biostatistics
mark@biostat.ucsf.edu | Link
Genotype - phenotype association; comparing DNA fingerprints; analysis of gene expression / microarray data; statistical methods
Saunak Sen | Image
Associate Professor in Residence, Epidemiology and Biostatistics
sen@biostat.ucsf.edu |
Genetic analysis of complex traits, statistical genetics/genomics, Bayesian statistics, statistical computing
Brian Shoichet | Image
Professor, Pharmaceutical Chemistry
shoichet@cgl.ucsf.edu | Shoichet Lab
Molecular docking, structure-based inhibitor discovery, beta-lactamase activity-stability-evolution, and crystallography.
Chao Tang | Image
Professor, Bioengineering and Therapeutic Sciences & Biochemistry and Biophysics
chao.tang@ucsf.edu | Tang Lab
Design and organization principles of biological systems; quantitative study and systems analysis of biological networks; systems biology.
Christopher Voigt | Image
Associate Professor, Pharmaceutical Chemistry
cavoigt@picasso.ucsf.edu | Voigt Lab
Design and evolution of gene circuits and pathways.
Jeff Wall | Image
Assistant Professor, Institute for Human Genetics
wallj@humgen.ucsf.edu
Evolutionary and Human Genetics